Evgenii O. Tretiakov

This study identifies S100A6 as a signaling molecule released by astrocytes that modulates neuronal development by inhibiting CaCyBp-mediated signaling, affecting proteostasis and neuritogenesis.

The paper demonstrates Fam150b and Alk expression in the PVN of adult mice, shows their exclusive expression in CRH neurons, and finds stress-induced upregulation of Fam150b mRNA.

The paper investigates the role of mitochondrial DNA repeats in aging and healthspan, finding that disrupting the common repeat reduces somatic deletions and improves healthspan.

The paper identifies a contact zone in the human mitochondrial genome where deletions are more likely, linking it to aging and lifespan.

This study demonstrates that BH4 deficiency exacerbates PD-related stressors and that BH4 augmentation protects dopaminergic neurons in multiple models.

The paper identifies an AH>GH substitution signature in mtDNA linked to aging and TSSS, showing higher frequency in species with longer generation lengths.