Depletion-assisted multiplexed cell-free RNA sequencing reveals distinct human and microbial signatures in plasma versus extracellular vesicles
Hongke Wang, Qing Zhan, Meng Ning…·Zhi Lü
The paper develops DETECTOR-seq to analyze fragmented cell-free RNAs in plasma and extracellular vesicles, revealing distinct RNA distributions and potential biomarkers for cancer detection.