Author

Razie Yousefi

The University of Texas Medical Branch at GalvestonORCID 0000-0003-4345-5032Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Organism:yeast· 2 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

Maga RowickaiD· 2 shared

Activity by Year

2019-2024 · peak 1/yr

2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintMay 24, 2024

Computer simulations reveal mechanisms of spatio-temporal regulation of DNA replication

Razie Yousefi, Maga Rowicka

The paper introduces RepliSim, a computer model of DNA replication that reveals how checkpoint mutations and dNTP levels affect origin activation and replication fork dynamics.

DOI 10.1101/2024.05.24.595841

yeastsimulation

𝕏 PostBluesky

BioinformaticsPLoS Computational BiologyPeer-reviewedDec 23, 2019

Stochasticity of replication fork speed plays a key role in the dynamics of DNA replication

Razie Yousefi, Maga Rowicka

This paper introduces a computational model of DNA replication that incorporates stochastic fork speed, showing it better reconstructs replication dynamics than models with constant speed.

13 citations

yeaststatistical model

𝕏 PostBluesky