ImmunologybioRxivPreprint
RNA splicing dynamics in CD8 T cells uncovers isoforms that impact T cell-mediated cancer immunotherapy
Shay Tzaban, Priyanga Appasamy, Elad Zisman…·Michal Lotem
The paper constructs a single-cell splicing atlas of human CD8 T cells and identifies isoform-specific immune checkpoints that enhance effector function and tumor control.