Li Guo

The paper develops a 27-color spectral flow cytometry protocol to quantify platelet-leukocyte aggregates across multiple leukocyte subsets in human whole blood, revealing their distribution and behavior in health and disease.

The paper describes a cell and gene therapy approach using GDF11-secreting cells to treat age-related pulmonary fibrosis, showing improved tissue repair and reduced fibrosis.

This study shows that substrate stiffness influences doxorubicin-induced senescence and secretory profiles in human pulmonary fibroblasts, with collagen enrichment observed in high-stiffness conditions.