Author

Stefan Freigang

University of BernORCID 0000-0003-4438-7828Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:human· 1 Approach:optimal transport· 1 Assay:scRNA-seq· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Ariadna Acedo-TerradesiD· 1 shared Inti ZlobeciD· 1 shared Jose F Carreno MartineziD· 1 shared María Rodríguez MartíneziD· 1 shared Minna Unelma KaikkoneniD· 1 shared Philipp KirchneriD· 1 shared Sergio Vazquez Montes de OcaiD· 1 shared Siting Wei· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperBioinformatics

Ariadna Acedo-TerradesORCID

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1 paper

Recent·Most cited

Cross-Cohort Optimal Transport Maps Macrophage Plasticity and Competing Routes to Inflammation and Fibrosis in Human Atherosclerotic Plaques

Sergio Vazquez Montes de Oca, Ariadna Acedo-Terrades, Jose F Carreno Martinez, Philipp Kirchner, Tiit Örd, Minna Unelma Kaikkonen, Siting Wei, Stefan Freigang, Inti Zlobec, María Rodríguez Martínez

The paper develops a computational framework using optimal transport to analyze macrophage state transitions in atherosclerosis, identifying origin-dependent plasticity mechanisms and shared regulatory circuits in inflammation and fibrosis.

bioRxiv · Aug 20, 2026 · PreprintBioinformatics