Author

David Adrian Merle

Medical University of GrazORCID 0000-0003-4485-5580Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:imaging· 1

Frequent Co-Authors

Angela ArmentoiD· 1 shared Christoph BrauniD· 1 shared Ellen KilgeriD· 1 shared Francesca ProvenzanoiD· 1 shared Giulia RighettiiD· 1 shared Katarína ŠtingliD· 1 shared Krunoslav T. StingliD· 1 shared Lasse WolframiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Angela ArmentoORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintNov 14, 2025

Fixel-Based Analysis reveals microstructural visual pathway changes associated with retinal remodeling in retinitis pigmentosa

Giulia Righetti, Veronica Cuevas Villanueva, Milda Reith…·Krunoslav T. Stingl

This study uses multimodal imaging to show microstructural changes in visual pathways associated with retinal remodeling in retinitis pigmentosa.

DOI 10.1101/2025.11.14.688435

𝕏 PostBluesky

Molecular BiologyAntioxidantsPeer-reviewedDec 3, 2021

mTOR inhibition via Rapamycin treatment partially reverts the deficit in energy metabolism caused by FH loss in RPE cells

David Adrian Merle, Francesca Provenzano, Mohamed Ali Jarboui…·Marius Ueffing

This study shows that mTOR inhibition with rapamycin partially rescues metabolic defects in RPE cells caused by CFH loss, suggesting a link between intracellular FH and the ubiquitin-proteasomal pathway.

26 citations

humanbulk RNA-seq

𝕏 PostBluesky