Author

Francesca Provenzano

German Center for Neurodegenerative DiseasesORCID 0000-0001-9171-564XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Michela DeleidiiD· 2 shared Angela ArmentoiD· 1 shared Carmela GiachinoiD· 1 shared Christin WeisslederiD· 1 shared David Adrian MerleiD· 1 shared Ellen KilgeriD· 1 shared Insa Hirschberg· 1 shared Linda OttoboniiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersNeuroscience

Michela DeleidiORCID

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2 papers

Recent·Most cited

NeuroscienceGliaPeer-reviewedSep 1, 2025

C9orf72 Repeat Expansion Induces Metabolic Dysfunction in Human iPSC- Derived Microglia and Modulates Glial-Neuronal Crosstalk

Marika Mearelli, Insa Hirschberg, Christin Weissleder…·Michela Deleidi

This study investigates how C9orf72 repeat expansion affects metabolism in human iPSC-derived microglia and its impact on glial-neuronal interactions in ALS.

3 citations

humanbulk RNA-seq

𝕏 PostBluesky

Molecular BiologyAntioxidantsPeer-reviewedDec 3, 2021

mTOR inhibition via Rapamycin treatment partially reverts the deficit in energy metabolism caused by FH loss in RPE cells

David Adrian Merle, Francesca Provenzano, Mohamed Ali Jarboui…·Marius Ueffing

This study shows that mTOR inhibition with rapamycin partially rescues metabolic defects in RPE cells caused by CFH loss, suggesting a link between intracellular FH and the ubiquitin-proteasomal pathway.

26 citations

humanbulk RNA-seq

𝕏 PostBluesky