NeurosciencePLoS ONEPeer-reviewed
Layer V Neocortical Neurons From Individuals With Drug-Resistant Epilepsy Show Multiple Synaptic Alterations but Lack Somatic Hyperexcitability
Luis Alfredo Márquez, Christopher Martínez-Aguirre, Estefanía Gutiérrez-Castañeda…·Emilio J. Galván
The paper examines synaptic and electrophysiological properties of layer V pyramidal neurons in drug-resistant epilepsy patients, finding synaptic alterations rather than somatic hyperexcitability contribute to seizure activity.
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