Erica D. Watson

This study shows that folate depletion in culture medium alters mouse trophoblast stem cell differentiation and endoreduplication.

This study investigates the epigenetic effects of one-carbon metabolism disruption in mouse placentas, revealing genome-wide methylation instability and potential transgenerational epigenetic mechanisms.

This study shows that disrupted folate metabolism in mice causes conceptus misalignment and developmental issues across generations, independent of maternal uterine factors.

The paper shows that defective folate metabolism leads to germline epigenetic instability and identifies Hira transcript expression as a biomarker for maternal phenotypic inheritance.