Weigang Qiu

This study shows bacterial sialidases remove sialic acids from complement proteins, reducing complement activation and helping bacteria evade immune detection.

This study generates trypanosome-resistant murine models expressing primate APOL1 proteins to investigate their role in immunity, finding that baboon APOL1 provides partial protection but with limited expression, while a chimeric APOL1 variant shows protection with a fitness cost.