Evolutionary BiologyNature Ecology & EvolutionPeer-reviewed
Intracellular interactions shape antiviral resistance outcomes in poliovirus via eco-evolutionary feedback
Alexander James Robertson, Benjamin Kerr, Alison F. Feder
This paper develops an intra-host eco-evolutionary model of poliovirus under pocapavir treatment, showing that antiviral potency must balance immediate viral suppression with preserving coinfection to prevent resistance.
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