Author

Lillian M. Daughrity

Mayo ClinicORCID 0000-0003-4644-7265Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Adrian M. IsaacsiD· 1 shared Ahad A. RahimiD· 1 shared Alessia Fisher· 1 shared Alexander J. CammackiD· 1 shared Alexander McGowniD· 1 shared Alla MikheenkoiD· 1 shared Alyssa N. CoyneiD· 1 shared Benedikt V. Hölbling· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Adrian M. IsaacsORCID

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1 paper

Recent·Most cited

NeuroscienceNature CommunicationsPeer-reviewedJan 8, 2025

Dual-targeting CRISPR-CasRx reduces C9orf72 ALS/FTD sense and antisense repeat RNAs in vitro and in vivo

Liam Kempthorne, Deniz Vaizoglu, Alexander J. Cammack…·Adrian M. Isaacs

This study demonstrates that CRISPR-CasRx reduces C9orf72 repeat RNAs and DPRs in vitro and in vivo, suggesting its therapeutic potential for ALS/FTD.

27 citationstop 1%

humanmouse

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