Author

Eric C. Chi

University of MinnesotaORCID 0000-0003-4647-0895Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:clustering· 1 Research Focus:deconvolution· 1 Organism:human· 1 Research Focus:spatial domain detection· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Wenyi WangiD· 2 shared Emilie MontellieriD· 1 shared Hao YaniD· 1 shared Haoming ShiiD· 1 shared Pierre L. HainautiD· 1 shared Qian TangiD· 1 shared Xiaoqian LiuiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 16 mutual co-author links

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2 shared papersBioinformatics

Wenyi WangORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintMay 20, 2026

The ATLAS Penalty: Auxiliary-Transformed Location-Aware Smoothing with Applications to Spatial Transcriptomics

Qian Tang, Eric C. Chi, Wenyi Wang

The paper introduces the ATLAS penalty for spatially smooth deconvolution in spatial transcriptomics, showing improved spatial domain detection using auxiliary covariates.

DOI 10.64898/2026.05.18.725545

spatial transcriptomicsstatistical model

𝕏 PostBluesky

GeneticsbioRxivPreprintOct 6, 2025

Transfer Learning for Survival-based Clustering of Predictors with an Application to TP53 Mutation Annotation

Xiaoqian Liu, Hao Yan, Haoming Shi…·Wenyi Wang

The paper develops TLSCP, a transfer learning method for survival-based clustering of predictors, applied to TP53 mutation annotation, showing improved clustering and clinical interpretability.

DOI 10.1101/2025.10.06.680732

humanstatistical model

𝕏 PostBluesky