Author

Yunmei Chen

BGI Group (China)ORCID 0000-0003-4656-8251Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 3 Research Focus:differential expression· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:variant calling· 2 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Zhiyu PengiD· 3 shared Zhonghua WangiD· 3 shared Jun SuniD· 2 shared Lijie SongiD· 2 shared Xiaoru Yang· 2 shared Xunzhe Yang· 2 shared Yi DaiiD· 2 shared Ziying YangiD· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersGenetic & Genomic Medicine

Zhiyu PengORCID

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3 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintDec 21, 2023

Whole genome and transcriptome sequencing in neuromuscular disorders: a diagnostic and health economic analysis

Ziying Yang, Xiaoru Yang, Yunmei Chen…·Yi Dai

This paper evaluates the clinical and cost-effectiveness of combining whole-genome and RNA sequencing for diagnosing neuromuscular disorders in patients with negative whole-exome results.

DOI 10.1101/2023.12.21.23300182

humanwhole-exome sequencing

𝕏 PostBluesky

Genetic & Genomic MedicinemedRxivPreprintApr 22, 2023

Systematic evaluation of the two main blood-based RNA-seq approaches for Mendelian disease diagnosis

Ziying Yang, Xiaoru Yang, Yunmei Chen…·Yi Dai

This study evaluates two RNA-seq methods for Mendelian disease diagnosis using blood samples, finding polyA-selection outperforms rRNA depletion in detecting disease-related genes and variants.

2 citations

humanbulk RNA-seq

𝕏 PostBluesky

BioinformaticsbioRxivPreprintOct 13, 2021

PSEA: A phenotypic similarity ensemble approach for prioritizes candidate genes to aid mendelian disease diagnosis

Zhonghua Wang, Lipei Liu, Chao Chen…·Zhiyu Peng

PSEA prioritizes candidate genes for mendelian disease diagnosis by improving phenotypic similarity evaluation using HPO terms and showing better performance than existing methods.

DOI 10.1101/2021.10.13.464308

statistical modelgene regulatory network inference

𝕏 PostBluesky