BiophysicsStructurePeer-reviewed
Cryo-EM Structures of Clostridium perfringens Enterotoxin Bound to its Human Receptor, Claudin-4
Sewwandi S. Rathnayake, Satchal K. Erramilli, Anthony A. Kossiakoff, Alex J. Vecchio
This study presents cryo-EM structures of Clostridium perfringens enterotoxin bound to claudin-4, revealing its pore assembly mechanism and potential therapeutic strategies.