Transcriptional profile of ribosome-associated quality control components and their associated phenotypes in mammalian cells
Otávio Augusto L. dos Santos, Rodolfo Lopes Carneiro, Rodrigo Dias Requião, Marcelo Ribeiro Alves, Tatiana Domitrovic, Fernando Lucas Palhano
The paper examines RQC gene expression and phenotypes across human tissues, finding widespread expression and mild effects of RQC silencing, with TCF25 showing mRNA-protein discordance due to proteasomal degradation.
Scientific Reports · Jan 16, 2024Peer-reviewedBioinformatics