Fernando Lucas Palhano

The paper investigates human transcripts enriched in PTMD codons and finds they have longer half-lives, suggesting PTMD selectively destabilizes otherwise stable mRNAs.

The paper analyzes ribosome profiling and RNA-seq data to show that translation efficiency in yeast changes during heat shock, differing from bacterial responses.

The paper examines RQC gene expression and phenotypes across human tissues, finding widespread expression and mild effects of RQC silencing, with TCF25 showing mRNA-protein discordance due to proteasomal degradation.

The paper examines gene-expression variation in human hearts, identifying highly variable genes linked to immune response and disease phenotypes.

The paper identifies a conserved positively charged arginine-rich domain in icosahedral viruses that correlates with capsid assembly and genome packaging strategies.

The paper examines how the first five codons affect translation efficiency in E. coli by comparing GFP library data with endogenous gene expression.

The paper evaluates mRNA half-life measurement methods in yeast and introduces the codon stabilization coefficient (CSC) as a predictor of codon bias and its effects on translation.