wavess 1.2: Presenting an HLA-aware within-host virus sequence simulation framework
wavess 1.2 simulates within-host virus sequences with an HLA-aware CTL response and variable recombination rate to improve accuracy in immune-dominated regions.
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Los Alamos National LaboratoryORCID 0000-0003-4674-2176Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
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wavess 1.2 simulates within-host virus sequences with an HLA-aware CTL response and variable recombination rate to improve accuracy in immune-dominated regions.
Zena Lapp, Hyejin Yoon, Brian Thomas Foley, Thomas Leitner
Hypermut 3 detects hypermutation patterns in sequences, handling multistate characters and gaps, and is available as a web and command-line tool.
Sophie Bérubé, Elizabeth Freedman, Diana Menya…·Amy Wesolowski
The paper identifies superinfection as a key mechanism in sustaining complex Plasmodium falciparum infections in mosquitoes by analyzing genetic diversity in a longitudinal cohort.
Katie Saund, Zena Lapp, Stephanie N. Thiede…·Evan S. Snitkin
This paper introduces prewas, an R package that standardizes variant pre-processing for bacterial GWAS to improve reproducibility and interpretability of results.