Synthetic BiologybioRxivPreprint
DeepSeMS: a large language model reveals hidden biosynthetic potential of the global ocean microbiome
Tingjun Xu, Yuwei Yang, Ruixin Zhu…·Na Jiao
DeepSeMS uses a large language model to predict chemical structures of secondary metabolites from microbial gene clusters, outperforming existing methods and discovering novel compounds in the ocean microbiome.