NeuroscienceActa NeuropathologicaPeer-reviewed
TMEM106B modifies TDP-43 pathology in human ALS brain and cell-based models of TDP-43 proteinopathy
Fei Mao, John L. Robinson, Travis L. Unger…·Alice S. Chen‐Plotkin
This study investigates how TMEM106B and C9orf72 genetic variants influence TDP-43 pathology in ALS and FTLD-TDP, finding TMEM106B modifies TDP-43 aggregation severity.
28 citations