Michael J. Satlin

This study characterizes 30 lytic Klebsiella pneumoniae bacteriophages, finding diverse genomic structures and no virulence or antibiotic resistance genes, with potential as antimicrobial agents against carbapenem-resistant K. pneumoniae.

The paper introduces Coffee-seq, a metagenomic DNA sequencing method that reduces environmental contamination, and applies it to detect infections and microbial signatures in clinical samples.

The paper uses bacterial Hi-C to study horizontal gene transfer of mobile antibiotic resistance genes in gut microbiomes, finding distinct HGT networks between individuals and increased dispersal in neutropenic patients.