Ilana Brito

Integrated multi-omics profiling of gut bacterial extracellular vesicles links cargo composition to host transcriptional responses

The paper profiles gut bacterial extracellular vesicles (bEVs) and links their cargo composition to host transcriptional responses across different cell types.

Rheinheimera sp. T2C2 Bacterial Biofilm for Bioremediation of Cobalt (II)

This study isolates and characterizes Rheinheimera sp. T2C2, a non-pathogenic bacterium capable of effectively biosorbing cobalt, with potential for bioremediation and metal recycling.

Environmental factors drive bacterial degradation of gastrointestinal mucus

This study shows that environmental factors, not glycan utilization, drive bacterial degradation of gastrointestinal mucus, with protease activity and nutrient/oxygen conditions playing key roles.

Characterization of gut microbiomes in rural Honduras reveals novel species and associations with human genetic variation

The paper characterizes gut microbiomes in rural Honduras, identifying novel species and host-microbiome associations through metagenomic sequencing and genomic data integration.

High Resolution Spatial Mapping of Microbiome-Host Interactions via in situ Polyadenylation and Spatial RNA Sequencing

The paper introduces a method to map microbiome-host interactions in the gut at high spatial resolution using in situ polyadenylation and spatial RNA sequencing, revealing microbial biogeography and host-microbe interactions in a mouse model.

Segatella copri strains adopt distinct roles within a single individual's gut

The paper isolates and compares 63 Segatella copri strains from a single gut microbiome, revealing phenotypic and host-microbe interaction differences.

Chemoproteomic profiling of substrate specificity in gut microbiota-associated bile salt hydrolases

The paper identifies gut microbiota-associated bile salt hydrolases (BSHs) with distinct substrate preferences using chemoproteomic profiling.

scMicrobe PTA: Near Complete Genomes From Single Bacterial Cells

This study introduces PTA, a single-cell amplification technique that produces nearly complete bacterial genomes and improves viral and gene cluster recovery compared to standard methods.

Engineering Bacterial Biomanufacturing: Characterization and Manipulation of Sphingomonas sp. LM7 Extracellular Polymers

This paper identifies and characterizes a novel bacterial polysaccharide, promonan, and presents methods to manipulate its properties and shorten purification time.

Widespread transfer of mobile antibiotic resistance genes within individual gut microbiomes revealed through bacterial Hi-C

The paper uses bacterial Hi-C to study horizontal gene transfer of mobile antibiotic resistance genes in gut microbiomes, finding distinct HGT networks between individuals and increased dispersal in neutropenic patients.

24-hour multi-omics analysis of residential sewage reflects human activity and informs public health

This study analyzes 24-hour residential sewage using untargeted genomics and metabolomics to identify human-derived biomarkers and inform public health.