Sarah McCann

This paper reports a two-center preclinical trial of JM-20, a benzodiazepine-dihydropyridine hybrid, showing modest neuroprotective effects in some rodent models of ischemic stroke but not in others.

This paper argues for embracing heterogeneity in preclinical research to improve reproducibility and generalizability through meta-analysis of phenotypic variability in ischaemic stroke models.

This paper compares statistical methods for meta-analysis of animal studies, finding that normalized mean difference (NMD) has higher power than standardized mean difference (SMD), and meta-regression outperforms stratified meta-analysis.