Author

Tomo Shiota

Nara Medical UniversityORCID 0000-0003-4742-3839Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:differential expression· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1

Frequent Co-Authors

Eiichiro MoriiD· 3 shared Kazuma SugieiD· 3 shared Hitoki NanauraiD· 2 shared Mari NakanishiiD· 2 shared Masaya MatsubayashiiD· 2 shared Naohiko IguchiiD· 2 shared Naritaka MorikawaiD· 2 shared Pattama WiriyasermkuliD· 2 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Eiichiro MoriORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintMar 31, 2020

Oxygen-glucose deprivation and reoxygenation on human cerebral organoids alters expression related to lipid metabolism

Naoki Iwasa, Takeshi K. Matsui, Naritaka Morikawa…·Kazuma Sugie

This study examines the effect of oxygen-glucose deprivation and reoxygenation on human cerebral organoids, identifying 15 downregulated genes and pathways related to lipid metabolism and ischemic injury mechanisms.

1 citation

humanbulk RNA-seq

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Developmental BiologybioRxivPreprintNov 4, 2019

Brainstem organoids from human pluripotent stem cells contain neural crest population

Nobuyuki Eura, Takeshi K. Matsui, Joachim Luginbühl…·Eiichiro Mori

This study develops human brainstem organoids containing neural crest cells and various neuron types, validated by single-cell RNA sequencing, proteomics, and electrophysiology.

2 citations

humanscRNA-seq

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Molecular BiologybioRxivPreprintOct 21, 2019

Toxic PR poly-dipeptides encoded by the C9orf72 repeat expansion target Kapβ2 and dysregulate phase separation of low-complexity domains

Hitoki Nanaura, Honoka Kawamukai, Ayano Fujiwara…·Eiichiro Mori

This study shows that PR poly-dipeptides from C9orf72 repeat expansion bind Kapβ2 and disrupt FUS droplet melting, contributing to nucleocytoplasmic transport deficits in ALS.

2 citations

humanproteomics

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