Systems BiologyPLoS Computational BiologyPeer-reviewed
Rational Discovery of Dual-Action Multi-Target Kinase Inhibitor for Precision Anti-Cancer Therapy Using Structural Systems Pharmacology
Hansaim Lim, Di He, Yue Qiu…·Lei Xie
The paper develops a multi-target screening platform to discover dual-action drugs for cancer therapy, identifying levosimendan as a potential candidate that reduces heart failure risk and inhibits cancer growth.
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