Author

Bill R. Miller

A.T. Still UniversityORCID 0000-0003-4868-7692Unclaimed ORCID profile · follow to get notified of new preprints

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Neuroscience· 1

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Organism:human· 1 Approach:mixed model· 1

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Edward C. CooperiD· 1 shared Emma C. ThompsoniD· 1 shared

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2026-2026 · peak 1/yr

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1 shared paperNeuroscience

Edward C. CooperORCID

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1 paper

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NeuroscienceJournal of Biomolecular Structure and DynamicsPeer-reviewedFeb 11, 2026

Molecular dynamics of the pathogenic KCNQ2 variant G256W reveal mechanisms of channel dysfunction in epileptic encephalopathy

Emma C. Thompson, Edward C. Cooper, Bill R. Miller

The paper uses molecular dynamics simulations to analyze the KCNQ2 G256W variant, revealing structural changes in the pore domain that disrupt ion selectivity and contribute to epileptic encephalopathy.

1 citation

humanmixed model

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