Author

Emma C. Thompson

Baylor College of MedicineORCID 0009-0006-8524-6035Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:electronic health records· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:mixed model· 1

Frequent Co-Authors

Alfred L. GeorgeiD· 2 shared Edward C. CooperiD· 2 shared Aamir R. ZuberiiD· 1 shared Ana G. Chavez· 1 shared Anastasios V. TzingounisiD· 1 shared Anuraag Madabushi· 1 shared Atul MaheshwariiD· 1 shared Bereket Habte· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Alfred L. GeorgeORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

NeurosciencebioRxivPreprintSep 3, 2026

Elevated neuronal excitability and seizure susceptibility in a mouse model of SCN2A-related developmental and epileptic encephalopathy

Nicole A. Hawkins, Dennis M. Echevarria-Cooper, Erin E. Corbett…·Jennifer A. Kearney

This study creates a mouse model of SCN2A-related DEE and shows it exhibits neuronal hyperexcitability, seizure susceptibility, and responsiveness to phenytoin.

DOI 10.64898/2026.08.30.748006

mouseelectronic health records

𝕏 PostBluesky

NeuroscienceJournal of Biomolecular Structure and DynamicsPeer-reviewedFeb 11, 2026

Molecular dynamics of the pathogenic KCNQ2 variant G256W reveal mechanisms of channel dysfunction in epileptic encephalopathy

Emma C. Thompson, Edward C. Cooper, Bill R. Miller

The paper uses molecular dynamics simulations to analyze the KCNQ2 G256W variant, revealing structural changes in the pore domain that disrupt ion selectivity and contribute to epileptic encephalopathy.

1 citation

humanmixed model

𝕏 PostBluesky

NeuroscienceeLifePeer-reviewedJan 6, 2025

Plural molecular and cellular mechanisms of pore domain KCNQ2 encephalopathy

Timothy J Abreo, Emma C. Thompson, Anuraag Madabushi…·Edward C. Cooper

The paper investigates the molecular and cellular mechanisms of KCNQ2 encephalopathy through structural analysis, functional assays, and an animal model, revealing multiple pathogenic effects of the G256W variant.

5 citations

mouseelectronic health records

𝕏 PostBluesky