GenomicsG3 Genes Genomes GeneticsPeer-reviewed
Measuring genome sizes using read-depth, k-mers, and flow cytometry: methodological comparisons in beetles (Coleoptera)
James M. Pflug, Valerie Renee Holmes, Crystal Burrus…·David R. Maddison
The paper compares genome size estimation methods using read-depth, k-mers, and flow cytometry in beetles, finding that no single method performs well across all species and that sequence-based methods tend to underestimate genome sizes.
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