Author

Lieselotte S.M. Kreuk

University of WashingtonORCID 0000-0003-4906-039XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1

Frequent Co-Authors

Alex KangiD· 1 shared Andi LiuiD· 1 shared Asim K. BeraiD· 1 shared Buwei HuangiD· 1 shared David A. BakeriD· 1 shared Dionne K. VafeadosiD· 1 shared Gaurav BhardwajiD· 1 shared Gizem Gokce AlpkiliciD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperBiochemistry

Alex KangORCID

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1 paper

Recent·Most cited

BiochemistryAngewandte Chemie International EditionPeer-reviewedOct 21, 2025

De novo design of high-affinity miniprotein binders targeting Francisella tularensis virulence factor

Gizem Gokce Alpkilic, Buwei Huang, Andi Liu…·Gaurav Bhardwaj

The paper designs high-affinity miniprotein binders targeting Flpp3, a virulence factor of Francisella tularensis, using physics-based and deep-learning methods, achieving sub-nanomolar affinities.

3 citations

protein structuredeep learning

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