Author

Magali Mathieu

Sanofi (France)ORCID 0000-0003-4960-0632Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Frederico Nardi· 1 shared Géraldine Pénarier· 1 shared Jérôme Arigon· 1 shared Marianne Duhamel· 1 shared Maysoun Shomali· 1 shared Monsif Bouaboula· 1 shared Rosalía Arrebola· 1 shared Samir Jegham· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Frederico Nardi

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintDec 11, 2024

An NAMPT Inhibitor Decreases NAMPT Capture by an Antibody Directed against the 5-Phosphoribosyl-1-Pyrophosphate-Binding Loop: A Rational for an NAMPT Occupancy Assay

Maysoun Shomali, Sandrine Hilairet, Marianne Duhamel…·Monsif Bouaboula

This paper shows that an NAMPT inhibitor-RP adduct reduces NAMPT capture by an antibody targeting the PRPP-binding loop, enabling a method to assess NAMPT occupancy and correlate it with NAD levels and drug efficacy.

DOI 10.1101/2024.12.11.628028

humanexperimental assay

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