Author

August Guang

Brown UniversityORCID 0000-0003-4974-1873Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:differential expression· 1 Research Focus:genome assembly· 1 Organism:rat· 1 Assay:scRNA-seq· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Angela R StermeriD· 1 shared Casey W. DunniD· 1 shared Charles E. LawrenceiD· 1 shared Daniel J. SpadeiD· 1 shared Felipe ZapataiD· 1 shared Mark HowisoniD· 1 shared Poonam MehtaiD· 1 shared Saadhya Bahudodda· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPharmacology & Toxicology

Angela R StermerORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologyToxicological SciencesPeer-reviewedJul 28, 2026

Ethylene Glycol Monomethyl Ether Altered Rat Sperm Small RNAs with Critical Developmental Roles

Yuan Pu, August Guang, Xinran Qi…·Daniel J. Spade

This study shows EGME exposure alters sperm small RNA profiles in rats, with dose-dependent changes in miRNAs, piRNAs, and tsRNAs, potentially affecting embryonic development.

DOI 10.1093/toxsci/kfag091

ratscRNA-seq

𝕏 PostBluesky

BioinformaticsbioRxivPreprintOct 12, 2017

Revising transcriptome assemblies with phylogenetic information in Agalma1.0

August Guang, Mark Howison, Felipe Zapata…·Casey W. Dunn

The paper introduces treeinform, a module in Agalma1.0 that improves transcriptome assemblies by using phylogenetic analysis to correct gene misassignment errors.

6 citations

whole-genome sequencingstatistical model

𝕏 PostBluesky