Author

Alicia Lou

Consejo Superior de Investigaciones CientíficasORCID 0009-0000-0264-828XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 2

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Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Juan F. PoyatosiD· 2 shared Mónica ChagoyeniD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

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2 top collaborators · 1 mutual co-author link

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2 shared papersSystems Biology

Juan F. PoyatosORCID

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2 papers

Recent·Most cited

Systems BiologyPLoS Computational BiologyPeer-reviewedFeb 9, 2026

Cell atlases and the Developmental Foundations of the Phenotype

Alicia Lou, Mónica Chagoyen, Juan F. Poyatos

The paper introduces the [D]-[P] rule to quantify the relationship between developmental gene expression and phenotypic similarity, using C. elegans to show that genes with broad expression have systemic phenotypes and those with specific expression have specialized roles.

DOI 10.1371/journal.pcbi.1013944

C. elegansscRNA-seq

𝕏 PostBluesky

Systems BiologybioRxivPreprintNov 12, 2025

Redefining Housekeeping Genes in the Context of Vertebrate Development

Alicia Lou, Juan F. Poyatos, Mónica Chagoyen

The paper redefines housekeeping genes to include those essential across developmental stages, not just adult tissues, using zebrafish data.

DOI 10.1101/2025.11.12.687949

zebrafishbulk RNA-seq

𝕏 PostBluesky