Author

Perry R Loken

Mayo ClinicORCID 0009-0000-5181-4213Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-exome sequencing· 1 Organism:zebrafish· 1

Frequent Co-Authors

Devin OglesbeeiD· 2 shared Ankit SabharwaliD· 1 shared Anthony J. TreicheliD· 1 shared Bibekananda KariD· 1 shared Chris GriffithsiD· 1 shared Dan MasoniD· 1 shared Daniel G. MacArthuriD· 1 shared David A. van HeeliD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenetics

Devin OglesbeeORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

GeneticseLifePeer-reviewedNov 21, 2022

A Genetic Model Therapy Proposes a Critical Role for Liver Dysfunction in Mitochondrial Biology and Disease

Ankit Sabharwal, Mark D. Wishman, Roberto Lopez Cervera…·Stephen Carl Ekker

This paper presents a zebrafish model of Leigh Syndrome, demonstrating liver dysfunction's critical role in mitochondrial disease through genetic rescue.

9 citations

zebrafishexperimental assay

𝕏 PostBluesky

GeneticseLifePeer-reviewedMar 24, 2020

Deep phenotyping of a healthy human HAO1 knockout informs therapeutic development for primary hyperoxaluria type 1.

Tracy L. McGregor, Karen A. Hunt, Elaine Yee…·David A. van Heel

The paper identifies a healthy individual with complete HAO1 knockout, showing normal oxalate levels but elevated glycolate, supporting the safety of HAO1 inhibition for PH1 therapy.

59 citationstop 3%

humanwhole-exome sequencing

𝕏 PostBluesky