MicrobiologybioRxivPreprint
Single-cell analysis of West Nile virus infection in brain organoids identified a serine synthesis enzyme as a determinant of viral neural tropism and a druggable antiviral target
Michael Leitner, Lachlan De Hayr, Ziyao Zhao…·Andrii Slonchak
This study uses human cerebral organoids to identify PHGDH as a key metabolic factor enabling WNV infection and a potential drug target.