H. M. A. Mohit Chowdhury

HiCInterpolate interpolates Hi-C contact matrices between timestamps to generate high-resolution 3D genome structures, preserving key chromatin features.

Robin provides a platform to analyze and compare loop caller results using Large Language Models, offering visualization and metrics like recovery and overlap.

ScHiCAtt improves single-cell Hi-C resolution using attention mechanisms, outperforming existing methods across different organisms and downsampling conditions.

This study evaluates 22 chromatin loop calling methods using Hi-C data, identifies their strengths and weaknesses, and introduces a new robustness score for performance assessment.