BioinformaticsbioRxivPreprint
Computational Design of Novel Selective Phosphodiesterase 4B Inhibitors from Natural Products: An Integrated Machine Learning and Structure-Based Drug Discovery Approach
Samson Ayorinde Oni, Moyege Daniel Oyemomi, Adebowale Osho, Abdulmalik Abdulfatai
The paper identifies PDE4B-selective inhibitors from natural products using machine learning and molecular docking, highlighting LTS0048837 as a promising lead.
DOI 10.64898/2026.05.16.725619