Joshua D. Myers

SHERLOCK is a deep generative framework for single-cell perturbation analysis that learns interpretable perturbation representations and enables causal analysis of downstream effects.

LYNX is a deep generative model that integrates multimodal spatial data to model spatial dynamics and cell-cell interactions across tissues.

Echidna quantifies gene dosage effects on phenotypic plasticity by integrating scRNA-seq and WGS data to separate genetic from cell non-autonomous mechanisms.