BiophysicsbioRxiv
Insights into substrate binding and utilization by hyaluronan synthase
Zachery Stephens, Julia Karasinska, Jochen Zimmer
This study elucidates how hyaluronan synthase (HAS) discriminates between UDP-GlcA and UDP-GlcNAc substrates using cryo-EM and identifies the role of non-canonical acceptors in HA synthesis.
1 citation