Multi-omic characterization of axolotl perilymph-cerebrospinal fluid reveals shifts in composition during limb regeneration
Noah Lopez, Bingsen Zhang, Steven R. Shuken, Yudong Zhou, Duygu Payzin‐Dogru, Julia C. Paoli, Anthony E. Striker, S. Y. Celeste Wu, Tia S. Patel, Karly Chan, Sebastian Böhm, Hani D. Singer, Ashley R. Juarez, Ryan T. Kim, Laurel Shugart, , Jessica L. Whited
This study characterizes axolotl perilymph-cerebrospinal fluid (P-CSF) during limb regeneration, identifying proteomic and metabolomic changes associated with amputation.
bioRxiv · Aug 28, 2026 · PreprintSystems Biology