GenomicsbioRxivPreprint
Protein tyrosine phosphatase receptor type D - A convergent risk gene for MDD, BPD, and ADHD and regulator of dopaminergic neuroplasticity in reward associated circuits; A multivariate GWAS, brain tissue and cell type enrichment, and gene finemapping
Christopher Lawrence, Thomas Folkmann Hansen
This study identifies PTPRD as a shared risk gene for MDD, BPD, and ADHD through multivariate GWAS and proposes a mechanistic role in dopaminergic neuroplasticity.
DOI 10.1101/2025.09.17.676918