BioinformaticsbioRxivPreprint
Identifying intervention strategies from machine learning models with COALA: a counterfactual optimization framework
B. Han, Qingling Duan, Ting Hu
COALA identifies optimal counterfactual interventions for individuals using gradient boosted trees on NHANES data, achieving 85.4% accuracy in predicting feature changes.
DOI 10.1101/2025.07.18.664723