Arghamitra Talukder

This study evaluates AlphaGenome's ability to decode regulatory mechanisms in ALS, finding it fails to accurately recover variant effects and assign regulatory signals to correct genes.

The paper introduces CLADES, a contrastive learning method for differential splicing prediction using orthologous positive pairs, achieving strong performance in classification and regression tasks.

This paper introduces JOLI, a hierarchical model that improves RNA isoform quantification by integrating short-read and long-read data across multiple samples.

The paper investigates whether multi-modal data and auxiliary tasks improve inter-protein contact prediction, finding that multi-modal inputs enhance precision but auxiliary tasks have limited benefits.