BiophysicsbioRxivPreprint
Large-scale simulations reveal evolutionary constraints on intrinsically disordered regions imposed by full-length protein architecture
Yang Jiang, Xiaoyang Liu, Li Zhao, Zhong‐Yuan Lu
The paper uses large-scale simulations to show that intrinsically disordered regions in proteins are structurally and evolutionarily constrained by their full-length protein architecture.
DOI 10.64898/2026.02.27.708199