Khue P. Nguyen

This study investigates the distinct roles of VMP1 and TMEM41B in hepatic lipoprotein secretion and autophagy, showing that VMP1 has a more critical role in regulating these processes in MASLD.

The paper develops a framework to detect and trace somatic retrotransposition events in human tissues, identifying rare L1 insertions and improving detection accuracy.

NetworkVI integrates multi-omics data using a biologically informed variational autoencoder, enabling interpretable cell phenotyping and discovery of lineage-specific immune states.

The paper uses multi-omics analysis to show OGT regulates aneuploidy by fine-tuning multiple cellular pathways through O-GlcNAcylation.