Additivity of the genetic load is a product of both synergistic and antagonistic epistasis in Drosophila
Imran Sayyed, Halle McNamara, Troy Day, Adam K. Chippindale
The paper investigates epistatic interactions in Drosophila by analyzing inbreeding effects on pupal productivity and pupa-to-adult viability, finding synergistic and antagonistic epistasis in different traits.
bioRxiv · Nov 4, 2025 · PreprintEvolutionary Biology