Dingwen Su

The paper introduces easySHARE-seq, a method for simultaneous single-cell ATAC-seq and RNA-seq, showing improved transcript recovery and scalability in murine liver nuclei.

This study shows that G-quadruplexes regulate chromatin accessibility and gene expression in Bloom Syndrome by stabilizing G4s, which enhances chromatin accessibility and promotes gene expression in BLM-deficient cells.

The paper introduces a copy number normalization pipeline to distinguish differential signals in ATAC-seq and ChIP-seq driven by copy number differences from other factors.

This study introduces CITR-seq, a method for single-cell TCR sequencing, and shows genetic factors significantly shape TCR repertoires in mice.

The paper compares TCR loci in mice and related species, finding recent contraction in the variable gene cluster in Mus musculus castaneus and expression of atypically oriented variable genes.