Anthony Khairallah

The paper identifies microglia subsets in ALS brain and spinal cord, finding an undifferentiated phenotype and enrichment of interferon response microglia in aggressive cases.

The paper identifies disease-specific cell signatures in non-lesional brain tissue of MS patients using single-cell and spatial transcriptomics.

This study identifies disease-enriched microglial subsets and validates compounds that modulate their states using single-cell RNA sequencing and in vitro experiments.