Loss of the cytosolic DNA-sensing genes cGAS and STING1 inarmadillos (Cingulata)
Lillie Schaffer, Amanda Ivanoff, Frédéric Delsuc, Vincent J. Lynch
This study shows that CGAS and STING1 genes are pseudogenized in armadillos, suggesting alternative mechanisms for sensing dsDNA and possibly contributing to their cancer resistance.
bioRxiv · May 13, 2025 · PreprintEvolutionary Biology