Evolutionary BiologyBulletin of Mathematical BiologyPeer-reviewed
Probability of Antibiotic Resistance During Treatment in Stochastic PK/PD-Based Bacterial Model with Distinct Drug and Mutation Modes
Chimezie Izuazu, Cameron J. Browne
The paper develops a stochastic PK/PD model to calculate the probability of antibiotic resistance emergence during treatment, considering de novo mutations and drug modes of action.
DOI 10.1007/s11538-026-01729-w